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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK4
All Species:
30.61
Human Site:
T440
Identified Species:
51.79
UniProt:
Q13043
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13043
NP_006273.1
487
55630
T440
Y
E
F
L
K
S
W
T
V
E
D
L
Q
K
R
Chimpanzee
Pan troglodytes
XP_001153224
503
57116
T456
Y
E
F
L
K
S
W
T
V
E
D
L
Q
K
R
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
T440
Y
E
F
L
K
S
W
T
V
E
D
L
Q
K
R
Dog
Lupus familis
XP_534432
487
55507
T440
Y
E
F
L
K
S
W
T
V
E
D
L
Q
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI11
487
55523
T440
Y
E
F
L
K
S
W
T
V
E
D
L
Q
K
R
Rat
Rattus norvegicus
O54748
491
56103
D436
W
R
V
P
Q
D
G
D
F
D
F
L
K
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
E257
M
L
R
D
L
I
N
E
A
M
D
V
K
L
K
Chicken
Gallus gallus
Q5ZJK4
486
55318
S439
Y
E
F
L
K
T
W
S
V
D
E
L
Q
R
R
Frog
Xenopus laevis
Q6PA14
485
55246
A440
F
L
K
D
W
S
V
A
E
V
Q
L
K
L
N
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
G436
N
W
K
V
P
Q
D
G
D
F
D
F
L
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
Q502
Q
Q
Q
Q
Q
Q
Q
Q
Q
D
E
Q
H
L
A
Honey Bee
Apis mellifera
XP_393691
465
52970
A431
Q
R
M
A
N
L
D
A
E
M
E
R
E
I
D
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
T453
F
E
F
L
R
N
I
T
L
D
E
L
I
R
R
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
S441
F
D
F
L
K
Q
L
S
I
D
E
L
R
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.3
97.3
N.A.
97.3
78
N.A.
55.8
92.1
76.5
77
N.A.
45.4
62.4
52.3
64.9
Protein Similarity:
100
95.8
99.7
98.9
N.A.
98.5
89.6
N.A.
57.2
96.5
86.8
87.4
N.A.
58.5
77.8
68.4
79.1
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
66.6
13.3
13.3
N.A.
0
0
40
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
26.6
100
26.6
20
N.A.
26.6
13.3
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
15
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
15
0
8
15
8
8
36
50
0
0
0
8
% D
% Glu:
0
50
0
0
0
0
0
8
15
36
36
0
8
8
0
% E
% Phe:
22
0
58
0
0
0
0
0
8
8
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
8
0
0
0
8
8
0
% I
% Lys:
0
0
15
0
50
0
0
0
0
0
0
0
22
43
8
% K
% Leu:
0
15
0
58
8
8
8
0
8
0
0
72
8
22
8
% L
% Met:
8
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
8
8
0
0
0
0
0
0
8
15
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
8
8
8
15
22
8
8
8
0
8
8
43
0
0
% Q
% Arg:
0
15
8
0
8
0
0
0
0
0
0
8
8
15
58
% R
% Ser:
0
0
0
0
0
43
0
15
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
43
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
8
0
43
8
0
8
0
0
0
% V
% Trp:
8
8
0
0
8
0
43
0
0
0
0
0
0
0
0
% W
% Tyr:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _